4000 fu Nattokinase capsules for Cardiovascular Support | OEM manufactured
Product Overview:
Nattokinase is a protease extracted from natto, a traditional Japanese fermented food. It has the effect of dissolving fibrin and improving blood circulation.
Efficacy: Health Care Supplement
4000 fu Nattokinase capsules for Cardiovascular Support | OEM manufactured Details
Last updated: May 2026
| Product Name | Nattokinase capsules GMP certification | Reson |
| Appearance | capsules |
| Specification | 500mg/Cap,1000mg/Cap or as your request |
| Certification | ISO，Halal，HACCP |
| Keywords | Nattokinase capsules |
| Storage | Keep in a cool, dry, dark location in a tightly sealed container or cylinder. |
| Shelf Life | 24 Months |
Mechanism of Action
1. Fibrinolysis
- Nattokinase can directly break down fibrin, the main component of blood clots, while simultaneously activating plasminogen activator (t-PA) in the body, promoting the endogenous thrombolytic system and reducing blood viscosity.
2. Regulation of Blood Lipids and Blood Pressure
- Studies show that it may lower blood pressure by inhibiting angiotensin-converting enzyme (ACE) and improve hyperlipidemia by accelerating lipid metabolism.
3. Antiplatelet Aggregation
- It indirectly inhibits excessive platelet aggregation, reducing the risk of atherosclerosis.
- Standard capsules: many supplements label nattokinase activity in FU (fibrinolytic units) or FU per capsule rather than mg. Common dosages: 2,000–4,000 FU once daily or 2,000 FU twice daily; some protocols use up to 6,000 FU/day in divided doses. Follow product label and clinician advice.
- Timing: often taken on an empty stomach for systemic absorption; if GI upset occurs, take with food. Duration and regimen should be clinician‑guided for those with health conditions.
| OEM Service | ||||
| We offer OEM services, please contact us for more information>> | ||||
| Product Type | Capsules,Softgels,Tablets,Gummies,Liquid Drops,Gum,solid beverage and other customized products | |||
| Packaging | Bottles, Bags, Bulk, Blister packs, Custom | |||
| Formulas | Standard formulas or custom formulas | |||
| OEM service | Support OEM&ODM Custom service,Different Formula，Flavors, Shapes，Bottle ，Color | |||
Core Function Explained
Standardization of Nattokinase: Why is FU More Important Than Milligrams?
- Nattokinase is an enzyme, and its activity is far more important than its weight. FU (fibrinolytic activity units) is the standard unit for measuring nattokinase activity. 4000 FU is equivalent to approximately 100 mg of highly active nattokinase. When choosing a product, don't just look at the milligram count; look at the FU count.
The Relationship Between Nattokinase and Vitamin K2
- Natural natto contains vitamin K2, which promotes blood clotting, contradicting the "anticoagulant" effect of nattokinase. High-quality nattokinase supplements should remove vitamin K2 or clearly state its content.
How to choose high‑quality nattokinase capsules
- Activity labeling: prefer products that state fibrinolytic activity in FU per serving (e.g., 2,000 FU/capsule). Avoid vague “enzyme units” without FU reference.
- Purity & testing: request third‑party COA for enzyme activity (HPLC/assay), heavy metals, microbial limits and allergen testing (soy).
- Strain & manufacturing: supplier transparency on Bacillus subtilis natto strain, GMP manufacturing, and endotoxin testing are positives.
- Stability & formulation: enzymatic activity can decline—look for stability data, appropriate encapsulation (enteric if claimed), and expiration/batch numbers.
- Non‑GMO & allergen labeling: important for EU/UK/US buyers; clearly state “contains soy” or “soy‑free fermentation” if applicable.
- Certifications: GMP, ISO, and third‑party testing seals; for athletes check anti‑doping testing if relevant (Informed‑Sport/NSF notified).
Nattokinase vs Other Fibrinolytic Components
| Components | Mechanism of Action | Active Units | Stability |
| Nattokinase | Direct fibrinolysis + activates t-PA | FU | Moderate |
| Lumbrokinase | Direct fibrinolysis | U | Moderate |
| Bromelain | Anti-inflammatory, mild fibrinolysis | GDU | High |
| Serexinase | Anti-inflammatory, anti-swelling | U | Moderate |
FAQ
Q1: How much nattokinase activity is in each capsule?
- A: Each capsule contains 4000 FU (Fibrinolytic Units) of nattokinase – a high potency dose for cardiovascular and circulatory support. This is the active enzyme activity, not just weight.
Q2: Does this product contain vitamin K2?
- A: No. Our nattokinase is processed to remove naturally occurring vitamin K2, which can interfere with anticoagulant medications. This makes it safer for those concerned with vitamin K intake.
Q3: Can I take nattokinase with blood thinners (warfarin, aspirin)?
- A: Do not combine without physician supervision. Nattokinase has blood-thinning effects and may increase bleeding risk when combined with anticoagulants. Medical monitoring is essential.
Q4: How should I take nattokinase capsules?
- A: Take 1 capsule daily on an empty stomach (30 minutes before a meal or 2 hours after) for optimal absorption. Food can reduce enzyme activity.
Q5: Is this product vegan?
- A: Yes. We offer a vegan option with HPMC (vegetable cellulose) capsules. Standard capsules use gelatin – please specify your preference when ordering.
Why Choose ECO (Ausreson/Reson) for Your Health Journey?
- Certified Manufacturing Excellence: Our state-of-the-art facilities are GMP certified and FDA registered. We adhere to the strictest global production standards, ensuring every capsule, gummy, or tablet is free of contaminants.
- Pure, Traceable Ingredients: We partner with sustainable farms worldwide. From raw material sourcing to final bottling, our R&D team conducts rigorous third-party laboratory testing (SGS/Eurofins) to assess potency and purity.
- Global Efficacy: Our formulas have been successfully exported to over 50 countries, including the US, EU, and Australia, optimized to meet diverse international health regulations and consumer needs.
- Own Factory, Guaranteed Strength: We have a 500㎡ modern production base equipped with German-imported production lines and an ISO 9001 certified quality management system. Annual production capacity exceeds 5 million units, supporting flexible production and rapid delivery, with a 99.6% on-time order rate.
- Real Results, Real Stories: Based on clinical case studies and validated user testimonials, our products have proven to deliver the health benefits we promise.
- Expert Formulas: Our in-house team of nutritionists and chemists stays at the forefront, creating scientifically based and truly effective formulas.
Choosing us is not just choosing a product, but partnering with a global company you can trust for the long term.
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OWN Brand
Intergroup is supplying OEM service for the Well-known brands Reson and Ausreson. Alibaba International Station No.1 supplier, Alibaba International Station Number 1, Alibaba International Station Number one Customized logo is welcome, Packing as your requirement. offering private label
Cusrom Process
01 Contact us 02 Confirm Product Formula 03 Sample Confirmation 04 Deposit Payment 05 Factory Production 06 Product Quallty Inspectlon 07 Balance Payment 08 Dispatch and Delvery
Factory & Exhibition
Private Label design, fast delivery, USA Warehouse, European Warehouse, capsules factory,Softgels factory,tablets factory, pills factory, Gummies factory, Liquid Drops factory,Gum factory,solid beverage factory, customized factory, capsules manufacturer, Softgels manufacturer, tablets manufacturer, pills manufacturer, Gummies manufacturer, Liquid Drops manufacturer,Gum manufacturer,solid beverage manufacturer.
In order to better serve our global customers, we will participate in various large-scale exhibitions.Europe, North America
Certifications
We are a nutritional supplement raw material and nutritional supplement brand OEM manufacturing factory in China with ISO 22000, ISO 9001, HACCP Management certifications, GMP certificate the factory, HALAL, CE, CE-ROHS, Organic, KOSHER, NSF Product certifications.Our product's comprehensive certification standards.
Packaging
We promise to provide high-quality products, but please raise any quality issues within 15 days of receiving the package.
From concept to finished product, we are committed to quality, efficiency, and customer satisfaction. Let us help you bring your product to life!
FAQs
Q: What kind of OEM forms can you supply ?
A: Pre mix powder, Capsules, Tablets, pills, Softgel,drops, Gummy.
Q: What's the pill size?
A: Capsule: 2#,1#,0#, 00#. Tablet: Can customize like 500mg, 1000mg, 1500mg, 2000mg
Q: What are capsule shells made of ?
A: Gelatin,HPMC (Vegan), Enteric gelatin & enteric vegan shells.
Q: Can the formula be customized by our Own Formula?
A: Yes, The formula can be exact customized.
Q: Minimum Order Quantity (MOQ) ?
A: Small quantity sample can be customized according to your requirements. Official order MOQ: 100,000 pieces
Q: Can you supply bottles with private label?
A: Yes, all can be customized.
Q: What kind of certificates can you supply for your OEM capsules / Tablets?
A: Health certificate, Original certificate.
