Akkermansia Muciniphila Gut Health capsules supplement

Last updated: October 2026

The Relationship Between Akkermansia and Disease

Obesity

• Gut microbiota play a crucial role in balancing health and disease. Akkermansia muciniphila, a type of gut microbiota, is a key organism at the interface between the intestinal lumen and host cell mucosa due to its ability to degrade intestinal mucosa. Akkermansia muciniphila is negatively correlated with obesity, diabetes, cardiovascular metabolic diseases, and low-grade inflammation. Oral administration of Akkermansia muciniphila can improve symptoms related to metabolic diseases in mice, and Akkermansia muciniphila shows promise as a candidate drug for treating type 2 diabetes and obesity.
• In recent years, several epidemiological and animal studies have demonstrated the important role of Akkermansia muciniphila in regulating metabolic disorders, including obesity, diabetes, liver disease, and cardiovascular disease. Based on these findings, some scholars have pointed out that Akkermansia muciniphila holds promise as a next-generation probiotic following lactobacilli and bifidobacteria.

Amyotrophic Lateral Sclerosis (ALS)

• Alan Ellinoff and his team at the Cancer-Microbiome Research Group of the German Cancer Research Center (DKFZ) discovered that increasing the concentration of Akkermansia myxophilus in a mouse model of ALS can improve symptoms and prolong survival.

Intestinal Cance

•  Researchers at Nanjing Medical University demonstrated in mouse experiments that oral administration of inactivated Akk bacteria [8] or the outer membrane protein Amuc_1100 of Akk bacteria can improve colitis by regulating CD8+ cytotoxic T cells (CTLs) and prevent the occurrence of related intestinal cancer.

Enteritis

• Akk bacteria, as a beneficial bacterium, gradually decreases as enteritis progresses. Supplementing with Akk bacteria or its outer membrane protein Amuc_1100 can alleviate enteritis symptoms, regulate immune responses in the spleen, intestines, and mesenteric lymph nodes, reduce intestinal inflammation levels, and prevent intestinal cancer caused by enteritis.

Key claimed benefits:

• Supports GLP-1 secretion, helping to regulate blood sugar and appetite.
• Enhances intestinal barrier function, reducing "leaky gut".
• Improves metabolic health, including reducing insulin resistance and regulating blood lipids.
• Has anti-inflammatory and immunomodulatory effects.

Dosage Form and Usage Recommendations

• Capsule Form: The most common form, convenient to take, often using delayed release or microencapsulation technology to improve intestinal colonization.
• Recommended Usage: Generally 1–2 capsules daily, taken on an empty stomach or before meals, depending on the product instructions.
• Stability: Most products are labeled as stable at room temperature and do not require refrigeration.

FAQ.

• Yes. Pasteurized Akkermansia muciniphila has been authorized as a Novel Food by the EFSA. Our products comply with these specific safety and dosage regulations.

• Our pasteurized AKK capsules are shelf-stable. Unlike traditional live probiotics that degrade in heat, our formula maintains potency at room temperature, making it ideal for international e-commerce and Amazon FBA.

• Absolutely. We specialize in blending AKK with synergistic ingredients like Berberine, Green Tea Extract (EGCG), or Chromium to create a comprehensive metabolic support supplement.

• We offer flexible tiers starting at 500 units for standardized formulas to help premium brands test the market.

OWN Brand

Intergroup is supplying OEM service for the Well-known brands Reson and Ausreson. Alibaba International Station No.1 supplier, Alibaba International Station Number 1, Alibaba International Station Number one Customized logo is welcome, Packing as your requirement. offering private label

Cusrom Process

01 Contact us 02 Confirm Product Formula 03 Sample Confirmation 04 Deposit Payment 05 Factory Production 06 Product Quallty Inspectlon 07 Balance Payment 08 Dispatch and Delvery

Factory & Exhibition

Private Label design, fast delivery, USA Warehouse, European Warehouse, capsules factory,Softgels factory,tablets factory, pills factory, Gummies factory, Liquid Drops factory,Gum factory,solid beverage factory, customized factory, capsules manufacturer, Softgels manufacturer, tablets manufacturer, pills manufacturer, Gummies manufacturer, Liquid Drops manufacturer,Gum manufacturer,solid beverage manufacturer.

In order to better serve our global customers, we will participate in various large-scale exhibitions.Europe, North America

Certifications

We are a nutritional supplement raw material and nutritional supplement brand OEM manufacturing factory in China with ISO 22000, ISO 9001, HACCP Management certifications, GMP certificate the factory, HALAL, CE, CE-ROHS, Organic, KOSHER, NSF Product certifications.Our product's comprehensive certification standards.

Packaging

We promise to provide high-quality products, but please raise any quality issues within 15 days of receiving the package.

From concept to finished product, we are committed to quality, efficiency, and customer satisfaction. Let us help you bring your product to life!

FAQs

Q: What kind of OEM forms can you supply ?
A: Pre mix powder, Capsules, Tablets, pills, Softgel,drops, Gummy.

Q: What's the pill size?
A: Capsule: 2#,1#,0#, 00#. Tablet: Can customize like 500mg, 1000mg, 1500mg, 2000mg

Q: What are capsule shells made of ?
A: Gelatin,HPMC (Vegan), Enteric gelatin & enteric vegan shells.

Q: Can the formula be customized by our Own Formula?
A: Yes, The formula can be exact customized.

Q: Minimum Order Quantity (MOQ) ?
A: Small quantity sample can be customized according to your requirements. Official order MOQ: 100,000 pieces

Q: Can you supply bottles with private label?
A: Yes, all can be customized.

Q: What kind of certificates can you supply for your OEM capsules / Tablets?
A: Health certificate, Original certificate.