Indole-3-Carbinol 400mg supplement OEM Wholesaler



Product Overview:
Indole-3-carbinol (I3C) is a naturally occurring plant compound, primarily derived from cruciferous vegetables (such as broccoli, cabbage, and kale). Its effects and functions mainly focus on antioxidation, hormone metabolism regulation, anticancer activity, and immune modulation. However, it should be noted that its mechanism of action and research evidence are largely based on laboratory or animal models, and further validation is needed for its clinical application in humans.
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Efficacy: Health Care Supplement
Indole-3-Carbinol 400mg supplement OEM Wholesaler Details
Last updated July 2026
| Product Name | Indole-3-Carbinol capsules OEM Wholesaler |
| Appearance | capsules |
| GMP certified factory | Xi'an ECO Biotech Factory Co., Ltd. Xi'an Henrikang Biotech Co., Ltd. |
| Brand | Reson and Ausreson |
| Specification | 500mg/Cap,1000mg/Cap or as your request |
| Certification | ISO,Halal,HACCP |
| Keywords | Indole-3-Carbinol capsules, indole 3 carbinol 300 mg, Best cruciferous extract for liver detox |
| Storage | Keep in a cool, dry, dark location in a tightly sealed container or cylinder. |
| Shelf Life | 24 Months |
How I3C Supports Estrogen Balance
To understand why health-conscious consumers search for this product, we must look at how the human body metabolizes estrogen. Estrogen is broken down via two primary pathways:
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The 2-hydroxyestrone (2-OHE1) pathway: Often referred to as the "good" or protective estrogen pathway.
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The 16-alpha-hydroxyestrone (16-alpha-OHE1) pathway: A pathway associated with hormone-sensitive tissue concerns when levels are disproportionately high.
Clinical studies show that Indole-3-Carbinol dietary supplements help safely shift the ratio of estrogen metabolites in favor of the protective 2-OHE1 pathway. By promoting healthy liver detoxification, I3C plays a critical role in supporting breast, cervical, and prostate cellular health.
Why Choose the Capsule Dosage Form?
When sourcing I3C, choosing the right delivery system is vital for product success and consumer compliance. While bulk powder is available, Indole-3-Carbinol capsules are the industry gold standard for several key reasons:
Raw I3C powder naturally possesses a strong, pungent, sulfur-like odor characteristic of cruciferous vegetables. High-quality Reson HPMC (vegetarian) or gelatin capsules securely lock in this odor, drastically improving the end-consumer experience and brand reviews.
I3C is highly sensitive to moisture, heat, and light. Raw powder can degrade quickly when exposed to air. Capsule shells act as a protective barrier, preserving the biological activity of the compound from production to consumption.
Standard therapeutic doses of I3C range from 200 mg to 400 mg daily. Capsules allow for exact pre-measured doses, eliminating the need for consumers to manually weigh or measure a volatile powder.
| OEM Service | ||||
| We offer OEM services, please contact us for more information>> | ||||
| Product Type | Capsules,Softgels,Tablets,Gummies,Liquid Drops,Gum,solid beverage and other customized products | |||
| Packaging | Bottles, Bags, Bulk, Blister packs, Custom | |||
| Formulas | Standard formulas or custom formulas | |||
| OEM service | Support OEM&ODM Custom service,Different Formula,Flavors, Shapes,Bottle ,Color | |||
Core Efficacy and Functions
- 1. Anti-cancer Potential: By regulating estrogen metabolism and promoting the production of 2-hydroxyestrone (a metabolite with low carcinogenic activity), it may reduce the risk of hormone-dependent cancers such as breast cancer and ovarian cancer. It induces cancer cell apoptosis, inhibits tumor angiogenesis, and blocks cancer cell proliferation signaling pathways (such as PI3K/AKT).
- 2. Antioxidant and Anti-inflammatory Effects: It activates the Nrf2 pathway, enhances cellular antioxidant capacity, and reduces free radical damage. It inhibits pro-inflammatory factors (such as NF-κB), alleviates chronic inflammation, and may have protective effects against cardiovascular diseases and neurodegenerative diseases.
- 3. Immune System Regulation: It enhances the activity of natural killer cells (NK cells) and T cells, improving antiviral and antitumor immune responses.
- 4. Endocrine Balance: It regulates estrogen levels and improves symptoms related to estrogen dominance (such as premenstrual syndrome and uterine fibroids).
- The Meal Rule: For best absorption and to prevent stomach sensitivity, take your I3C capsule with a meal containing healthy fats.
- Combine with standard B-Vitamins: B-vitamins (especially methylated Folate and B12) support the methylation cycle, which works hand-in-hand with I3C to clear hormones.
- Avoid Antacids: I3C requires stomach acid to convert into its active forms (like DIM). Avoid taking it at the exact same time as heavy antacids or PPI medications.
Frequently Asked Questions
Q: Why do my capsules smell like cabbage?
- A: This is standard for real I3C! The sulfur scent is the active ingredient working. If your I3C doesn't have a slight cruciferous smell, it likely isn't real or potent.
- A: One capsule of standardized I3C can provide the active nutrient equivalent of several pounds of raw broccoli, without the bloating and gas that comes from eating massive amounts of fiber.
- A: Yes. Our I3C is plant-derived and encapsulated in plant-based vegetable cellulose, making it 100% suitable for vegans and vegetarians.
- A: I3C is the "parent" compound. When you swallow I3C, your stomach acid converts it into DIM and several other beneficial compounds. Taking I3C provides a broader spectrum of cruciferous metabolites.
- A: Because I3C influences liver enzymes and hormone metabolism, we strongly recommend consulting your healthcare provider before combining it with any hormonal medications.

OWN Brand
Intergroup is supplying OEM service for the Well-known brands Reson and Ausreson. Alibaba International Station No.1 supplier, Alibaba International Station Number 1, Alibaba International Station Number one Customized logo is welcome, Packing as your requirement. offering private label

Cusrom Process
01 Contact us 02 Confirm Product Formula 03 Sample Confirmation 04 Deposit Payment 05 Factory Production 06 Product Quallty Inspectlon 07 Balance Payment 08 Dispatch and Delvery


Factory & Exhibition
Private Label design, fast delivery, USA Warehouse, European Warehouse, capsules factory,Softgels factory,tablets factory, pills factory, Gummies factory, Liquid Drops factory,Gum factory,solid beverage factory, customized factory, capsules manufacturer, Softgels manufacturer, tablets manufacturer, pills manufacturer, Gummies manufacturer, Liquid Drops manufacturer,Gum manufacturer,solid beverage manufacturer.
In order to better serve our global customers, we will participate in various large-scale exhibitions.Europe, North America

Certifications
We are a nutritional supplement raw material and nutritional supplement brand OEM manufacturing factory in China with ISO 22000, ISO 9001, HACCP Management certifications, GMP certificate the factory, HALAL, CE, CE-ROHS, Organic, KOSHER, NSF Product certifications.Our product's comprehensive certification standards.

Packaging
We promise to provide high-quality products, but please raise any quality issues within 15 days of receiving the package.
From concept to finished product, we are committed to quality, efficiency, and customer satisfaction. Let us help you bring your product to life!

FAQs
Q: What kind of OEM forms can you supply ?
A: Pre mix powder, Capsules, Tablets, pills, Softgel,drops, Gummy.
Q: What's the pill size?
A: Capsule: 2#,1#,0#, 00#. Tablet: Can customize like 500mg, 1000mg, 1500mg, 2000mg
Q: What are capsule shells made of ?
A: Gelatin,HPMC (Vegan), Enteric gelatin & enteric vegan shells.
Q: Can the formula be customized by our Own Formula?
A: Yes, The formula can be exact customized.
Q: Minimum Order Quantity (MOQ) ?
A: Small quantity sample can be customized according to your requirements. Official order MOQ: 100,000 pieces
Q: Can you supply bottles with private label?
A: Yes, all can be customized.
Q: What kind of certificates can you supply for your OEM capsules / Tablets?
A: Health certificate, Original certificate.







