Trimethylglycine TMG Betaine Capsules | methylation | Reson
Product Overview:
Trimethylglycine, often referred to as TMG or betaine, is not ordinary betaine—it is a precisely purified compound with specific biological activities. With the rise of functional medicine and personalized nutrition, more and more science-conscious consumers in Europe and America are seeking supplements with clearly defined mechanisms of action and dosage parameters. TMG capsules have won the favor of discerning consumers due to their precise methyl donor function, heart health support, and potential for athletic performance.
Efficacy: Health Care Supplement
Trimethylglycine TMG Betaine Capsules | methylation | Reson Details
| Product Name | Trimethylglycine TMG Capsules | methylation | Reson |
| Appearance | capsules |
| Specification | 500mg/Cap,1000mg/Cap or as your request |
| Certification | ISO，Halal，HACCP |
| Function |
Supports homocysteine metabolism |
| Keywords | Betaine anhydrous capsules, Methyl donor supplement, TMG benefits and side effects |
| Storage | Keep in a cool, dry, dark location in a tightly sealed container or cylinder. |
| Shelf Life | 24 Months |
Precise Chemical Properties and Bioavailability
Trimethylglycine (C5H11NO2) is unique in its molecular structure due to the three methyl (-CH3) groups. Unlike common betaine hydrochloride, pharmaceutical-grade TMG undergoes purification to ensure high concentration and low impurities. High-quality TMG capsules should clearly indicate:
- Purity Grade: Pharmaceutical-grade, typically ≥99% purity
- Molecular Form: Anhydrous, ensuring stability
- Methyl Donor Capacity per Serving: Approximately 12% usable methyl groups per 1000mg TMG
- Capsule Material: Plant cellulose capsules preferred by consumers in Europe and America, meeting vegetarian requirements.
Scientific Parameters of Mechanism of Action
The core function of TMG is as a "methyl donor," participating in key biochemical processes in the human body:
- Homocysteine Cycle Regulation: TMG converts homocysteine to methionine via the betaine-homocysteine methyltransferase (BHMT) pathway. Studies have shown that effective doses (typically 1.5-3 g/day) can support homocysteine levels within a healthy range.
- Liver Health Support: As an osmotic protectant, TMG helps maintain water balance at the cellular level, particularly in liver cells under stress.
- Relevance to Exercise Performance: Studies in active populations in Europe and America indicate that TMG may indirectly affect high-intensity training performance by optimizing creatine synthesis and supporting protein function.
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| Product Type | Capsules,Softgels,Tablets,Gummies,Liquid Drops,Gum,solid beverage and other customized products | |||
| Packaging | Bottles, Bags, Bulk, Blister packs, Custom | |||
| Formulas | Standard formulas or custom formulas | |||
| OEM service | Support OEM&ODM Custom service,Different Formula，Flavors, Shapes，Bottle ，Color | |||
Uses and Indications
1. Treatment of Metabolic Disorders
- Betaine is clinically used to treat hyperhomocysteinemia, a condition characterized by elevated homocysteine levels in the blood due to genetics or nutritional deficiencies. For example, it is used as adjunctive therapy in cystathionine β-synthetase deficiency (a rare genetic disorder) by promoting homocysteine metabolism to lower its concentration.
2. Digestive Health Support
- Betaine hydrochloride (Betaine HCl) is commonly used to improve indigestion caused by insufficient stomach acid. By supplementing stomach acid, it helps break down food, relieving bloating or stomach discomfort.
3. Sports and Nutritional Supplements
- As a methyl donor, betaine participates in methylation reactions in the body, supporting liver function, protein synthesis, and cell protection. Therefore, it is commonly found in sports nutrition supplements to enhance athletic performance or promote muscle recovery.
Frequently Asked Questions.
Q: Are Trimethylglycine and Betaine Hydrochloride the same?
- A: Although both are called "betaine," Trimethylglycine (TMG) is a specific trimethylglycine compound, while betaine hydrochloride usually refers to betaine hydrochloride, primarily used for digestive support. Their chemical structures and main uses differ.
Q: What is the special significance of TMG for people with a Western diet?
- A: Western diets tend to have higher animal protein intake, which may increase the metabolic burden of homocysteine production. As a methyl donor, TMG can support homocysteine metabolism, making it particularly suitable for active individuals with high-protein diets.
Q: What is the recommended dosage?
- A: Most studies indicate that the dosage range for maintaining healthy homocysteine metabolism is 1.5-3 grams/day, divided into 1-2 doses. It is recommended to start with a lower dose and adjust according to individual response and professional advice.
Q: Can I take TMG with my other supplements?
- A: TMG typically works synergistically with B vitamins (especially B6, B12, and folic acid) to form a complete methylation support regimen. However, it may interact with certain medications (such as anticoagulants); please consult a healthcare professional.
Q: How to assess the effectiveness of TMG supplements?
- A: In addition to subjective feelings (energy levels, exercise recovery), users in Europe and America often objectively assess the supplementation's effectiveness by regularly monitoring homocysteine levels, liver function indicators, and lipid profiles through blood tests.
Q: Is cycling (cyclical use) recommended?
- A: Some functional medicine experts recommend a cyclical pattern of 8-12 weeks of continuous use followed by a 4-6 week rest period to prevent decreased receptor sensitivity. Individual responses vary; please adjust according to your own situation.
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01 Contact us 02 Confirm Product Formula 03 Sample Confirmation 04 Deposit Payment 05 Factory Production 06 Product Quallty Inspectlon 07 Balance Payment 08 Dispatch and Delvery
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Private Label design, fast delivery, USA Warehouse, European Warehouse, capsules factory,Softgels factory,tablets factory, pills factory, Gummies factory, Liquid Drops factory,Gum factory,solid beverage factory, customized factory, capsules manufacturer, Softgels manufacturer, tablets manufacturer, pills manufacturer, Gummies manufacturer, Liquid Drops manufacturer,Gum manufacturer,solid beverage manufacturer.
In order to better serve our global customers, we will participate in various large-scale exhibitions.Europe, North America
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We are a nutritional supplement raw material and nutritional supplement brand OEM manufacturing factory in China with ISO 22000, ISO 9001, HACCP Management certifications, GMP certificate the factory, HALAL, CE, CE-ROHS, Organic, KOSHER, NSF Product certifications.Our product's comprehensive certification standards.
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FAQs
Q: What kind of OEM forms can you supply ?
A: Pre mix powder, Capsules, Tablets, pills, Softgel,drops, Gummy.
Q: What's the pill size?
A: Capsule: 2#,1#,0#, 00#. Tablet: Can customize like 500mg, 1000mg, 1500mg, 2000mg
Q: What are capsule shells made of ?
A: Gelatin,HPMC (Vegan), Enteric gelatin & enteric vegan shells.
Q: Can the formula be customized by our Own Formula?
A: Yes, The formula can be exact customized.
Q: Minimum Order Quantity (MOQ) ?
A: Small quantity sample can be customized according to your requirements. Official order MOQ: 100,000 pieces
Q: Can you supply bottles with private label?
A: Yes, all can be customized.
Q: What kind of certificates can you supply for your OEM capsules / Tablets?
A: Health certificate, Original certificate.
